![]() ![]() Obligatory to confirm MRD negativity in CR or sCR patientsĮvery 12 mo in CR and/or MRD-negative patients aĬytogenetics: karyotype and FISH for detection of del17p, t(4 14), t(14 16), ampl 1q/gain 1q, t(11 14) Optional (obligatory for nonsecretory disease) Obligatory to confirm CR or for nonsecretory MM Urine electrophoresis and IF electrophoresisīM cytology and biopsy to confirm plasmacytosis and monoclonality Urine sample from 24 h urine collection to check for proteinuria and light-chain proteinuria
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